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Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-induced circulatory and cardiac dysfunction is associated with high mortality rates. Mitophagy, a specific form of autophagy, is excessively activated in lipopolysaccharide-induced myo...

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Detalles Bibliográficos
Autores principales: Ji, Wenqing, Wan, Tiantian, Zhang, Fang, Zhu, Xiaomei, Guo, Shubin, Mei, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139555/
https://www.ncbi.nlm.nih.gov/pubmed/34025411
http://dx.doi.org/10.3389/fphar.2021.641058