Cargando…
Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
The antidiuretic hormone arginine-vasopressin (AVP) forms a signaling complex with the V2 receptor (V2R) and the G(s) protein, promoting kidney water reabsorption. Molecular mechanisms underlying activation of this critical G protein–coupled receptor (GPCR) signaling system are still unknown. To fil...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139594/ https://www.ncbi.nlm.nih.gov/pubmed/34020960 http://dx.doi.org/10.1126/sciadv.abg5628 |