Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex

The antidiuretic hormone arginine-vasopressin (AVP) forms a signaling complex with the V2 receptor (V2R) and the G(s) protein, promoting kidney water reabsorption. Molecular mechanisms underlying activation of this critical G protein–coupled receptor (GPCR) signaling system are still unknown. To fil...

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Detalles Bibliográficos
Autores principales: Bous, Julien, Orcel, Hélène, Floquet, Nicolas, Leyrat, Cédric, Lai-Kee-Him, Joséphine, Gaibelet, Gérald, Ancelin, Aurélie, Saint-Paul, Julie, Trapani, Stefano, Louet, Maxime, Sounier, Rémy, Déméné, Hélène, Granier, Sébastien, Bron, Patrick, Mouillac, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139594/
https://www.ncbi.nlm.nih.gov/pubmed/34020960
http://dx.doi.org/10.1126/sciadv.abg5628

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