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A Review of Alternative Treatment Options in Diabetic Polyneuropathy

Currently there is no recognized curative treatment for diabetic polyneuropathy (DPN). Strict glucose control and symptomatic pain relief are the first line management routes. DPN is a common complication of diabetes and has a major detrimental influence on the quality of life (QOL) for many patient...

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Autores principales: Zaheer, Arsalan, Zaheer, Faizan, Saeed, Hadia, Tahir, Zoya, Tahir, Muhammad Waqas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139599/
https://www.ncbi.nlm.nih.gov/pubmed/34040901
http://dx.doi.org/10.7759/cureus.14600
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author Zaheer, Arsalan
Zaheer, Faizan
Saeed, Hadia
Tahir, Zoya
Tahir, Muhammad Waqas
author_facet Zaheer, Arsalan
Zaheer, Faizan
Saeed, Hadia
Tahir, Zoya
Tahir, Muhammad Waqas
author_sort Zaheer, Arsalan
collection PubMed
description Currently there is no recognized curative treatment for diabetic polyneuropathy (DPN). Strict glucose control and symptomatic pain relief are the first line management routes. DPN is a common complication of diabetes and has a major detrimental influence on the quality of life (QOL) for many patients. Due to the scope of the problem, it is imperative that treatment options which impede DPN's progression and restore sensorineural function should be researched comprehensively and made available to the masses at an economical cost. We reviewed a multitude of atypical treatment options for DPN including capsaicin, lidocaine, acupuncture, electrical nerve stimulation, alpha lipoic acid, benfotiamine, and acetyl-l-carnitine and explored the evidence to date regarding their safety and efficacy. Most of these options have been around for a long time and have promising pilot studies or small-scale trials focused on DPN treatment.
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spelling pubmed-81395992021-05-25 A Review of Alternative Treatment Options in Diabetic Polyneuropathy Zaheer, Arsalan Zaheer, Faizan Saeed, Hadia Tahir, Zoya Tahir, Muhammad Waqas Cureus Endocrinology/Diabetes/Metabolism Currently there is no recognized curative treatment for diabetic polyneuropathy (DPN). Strict glucose control and symptomatic pain relief are the first line management routes. DPN is a common complication of diabetes and has a major detrimental influence on the quality of life (QOL) for many patients. Due to the scope of the problem, it is imperative that treatment options which impede DPN's progression and restore sensorineural function should be researched comprehensively and made available to the masses at an economical cost. We reviewed a multitude of atypical treatment options for DPN including capsaicin, lidocaine, acupuncture, electrical nerve stimulation, alpha lipoic acid, benfotiamine, and acetyl-l-carnitine and explored the evidence to date regarding their safety and efficacy. Most of these options have been around for a long time and have promising pilot studies or small-scale trials focused on DPN treatment. Cureus 2021-04-21 /pmc/articles/PMC8139599/ /pubmed/34040901 http://dx.doi.org/10.7759/cureus.14600 Text en Copyright © 2021, Zaheer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Zaheer, Arsalan
Zaheer, Faizan
Saeed, Hadia
Tahir, Zoya
Tahir, Muhammad Waqas
A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title_full A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title_fullStr A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title_full_unstemmed A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title_short A Review of Alternative Treatment Options in Diabetic Polyneuropathy
title_sort review of alternative treatment options in diabetic polyneuropathy
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139599/
https://www.ncbi.nlm.nih.gov/pubmed/34040901
http://dx.doi.org/10.7759/cureus.14600
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