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An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome

Testicular choriocarcinomas comprise less than 1% of all testicular tumors and are often highly vascular with early hematogenous metastasis. Choriocarcinoma syndrome (CS) is a rare entity distinguished by diffuse tumor burden and often fatal bleeding from metastatic sites. Most reported cases descri...

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Autores principales: Yoon, Jennifer, Hu, Steve, Farrell, Jessica, Shah, Kandarp K, Chintanaboina, Jaya Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139606/
https://www.ncbi.nlm.nih.gov/pubmed/34040900
http://dx.doi.org/10.7759/cureus.14599
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author Yoon, Jennifer
Hu, Steve
Farrell, Jessica
Shah, Kandarp K
Chintanaboina, Jaya Krishna
author_facet Yoon, Jennifer
Hu, Steve
Farrell, Jessica
Shah, Kandarp K
Chintanaboina, Jaya Krishna
author_sort Yoon, Jennifer
collection PubMed
description Testicular choriocarcinomas comprise less than 1% of all testicular tumors and are often highly vascular with early hematogenous metastasis. Choriocarcinoma syndrome (CS) is a rare entity distinguished by diffuse tumor burden and often fatal bleeding from metastatic sites. Most reported cases describe pulmonary hemorrhage secondary to initiation of chemotherapy. We present a fatal case of a young, previously healthy male with overwhelming gastrointestinal bleeding as the presenting sign of CS. Our case demonstrates that CS should be considered in the differential diagnosis for refractory anemia due to gastrointestinal hemorrhage in a young male with a testicular mass.
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spelling pubmed-81396062021-05-25 An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome Yoon, Jennifer Hu, Steve Farrell, Jessica Shah, Kandarp K Chintanaboina, Jaya Krishna Cureus Internal Medicine Testicular choriocarcinomas comprise less than 1% of all testicular tumors and are often highly vascular with early hematogenous metastasis. Choriocarcinoma syndrome (CS) is a rare entity distinguished by diffuse tumor burden and often fatal bleeding from metastatic sites. Most reported cases describe pulmonary hemorrhage secondary to initiation of chemotherapy. We present a fatal case of a young, previously healthy male with overwhelming gastrointestinal bleeding as the presenting sign of CS. Our case demonstrates that CS should be considered in the differential diagnosis for refractory anemia due to gastrointestinal hemorrhage in a young male with a testicular mass. Cureus 2021-04-20 /pmc/articles/PMC8139606/ /pubmed/34040900 http://dx.doi.org/10.7759/cureus.14599 Text en Copyright © 2021, Yoon et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Yoon, Jennifer
Hu, Steve
Farrell, Jessica
Shah, Kandarp K
Chintanaboina, Jaya Krishna
An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title_full An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title_fullStr An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title_full_unstemmed An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title_short An Exceptionally Rare Cause of Refractory Gastrointestinal Bleed: Choriocarcinoma Syndrome
title_sort exceptionally rare cause of refractory gastrointestinal bleed: choriocarcinoma syndrome
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139606/
https://www.ncbi.nlm.nih.gov/pubmed/34040900
http://dx.doi.org/10.7759/cureus.14599
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