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TLR3 Activation by Zika Virus Stimulates Inflammatory Cytokine Production Which Dampens the Antiviral Response Induced by RIG-I-Like Receptors

Infection with the Zika virus (ZIKV), a member of the Flaviviridae family, can cause serious neurological disorders, most notably microcephaly in newborns. In this study, we investigated the innate immune response to ZIKV infection in cells of the nervous system. In human neural progenitor cells (hN...

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Detalles Bibliográficos
Autores principales:	Plociennikowska, Agnieszka, Frankish, Jamie, Moraes, Thais, Del Prete, Dolores, Kahnt, Franziska, Acuna, Claudio, Slezak, Michal, Binder, Marco, Bartenschlager, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139665/ https://www.ncbi.nlm.nih.gov/pubmed/33658344 http://dx.doi.org/10.1128/JVI.01050-20

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