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Phase I Trial on Arterial Embolization with Hypoxia Activated Tirapazamine for Unresectable Hepatocellular Carcinoma

BACKGROUND: Tirapazamine (TPZ) is a hypoxia activated drug that may be synergistic with transarterial embolization (TAE). The primary objective was to evaluate the safety of combining TPZ and TAE in patients with unresectable HCC and determine the optimal dose for Phase II. METHODS: This was a Phase...

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Detalles Bibliográficos
Autores principales:	Abi-Jaoudeh, Nadine, Dayyani, Farshid, Chen, Pei Jer, Fernando, Dayantha, Fidelman, Nicholas, Javan, Hanna, Liang, Po-Chin, Hwang, Jen-I, Imagawa, David K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139681/ https://www.ncbi.nlm.nih.gov/pubmed/34041204 http://dx.doi.org/10.2147/JHC.S304275

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