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SARS-CoV-2 Rapidly Adapts in Aged BALB/c Mice and Induces Typical Pneumonia

Age is a risk factor for coronavirus disease 2019 (COVID-19)-associated morbidity and mortality in humans; hence, in this study, we compared the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in young and aged BALB/c mice. We found that SARS-CoV-2 isolates replicate...

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Detalles Bibliográficos
Autores principales:	Zhang, Yufei, Huang, Kun, Wang, Ting, Deng, Fei, Gong, Wenxiao, Hui, Xianfeng, Zhao, Ya, He, Xinlin, Li, Chengfei, Zhang, Qiang, Chen, Xi, Lv, Changjie, Lin, Xian, Yang, Ying, Sun, Xiaomei, Shi, Zhengli, Chen, Huanchun, Zou, Zhong, Jin, Meilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139693/ https://www.ncbi.nlm.nih.gov/pubmed/33692211 http://dx.doi.org/10.1128/JVI.02477-20

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