Thiopurines Activate an Antiviral Unfolded Protein Response That Blocks Influenza A Virus Glycoprotein Accumulation

Influenza A viruses (IAVs) utilize host shutoff mechanisms to limit antiviral gene expression and redirect translation machinery to the synthesis of viral proteins. Previously, we showed that IAV replication is sensitive to protein synthesis inhibitors that block translation initiation and induce th...

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Detalles Bibliográficos
Autores principales: Slaine, Patrick D., Kleer, Mariel, Duguay, Brett A., Pringle, Eric S., Kadijk, Eileigh, Ying, Shan, Balgi, Aruna, Roberge, Michel, McCormick, Craig, Khaperskyy, Denys A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139708/
https://www.ncbi.nlm.nih.gov/pubmed/33762409
http://dx.doi.org/10.1128/JVI.00453-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139708/
https://www.ncbi.nlm.nih.gov/pubmed/33762409
http://dx.doi.org/10.1128/JVI.00453-21

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