Cargando…
Urolithin A Inhibits Epithelial–Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway
PURPOSE: The epithelial-to-mesenchymal transition (EMT) is a fundamental process in tumor progression that endows cancer cells with migratory and invasive potential. Snail, a zinc finger transcriptional repressor, plays an important role in the induction of EMT by directly repressing the key epithel...
Autores principales: | Cheng, Feng, Dou, Jintao, Zhang, Yong, Wang, Xiang, Wei, Huijun, Zhang, Zhijian, Cao, Yuxiang, Wu, Zhihao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139733/ https://www.ncbi.nlm.nih.gov/pubmed/34040386 http://dx.doi.org/10.2147/OTT.S305595 |
Ejemplares similares
-
Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16(INK4a) inactivation
por: Li, Xiangrui, et al.
Publicado: (2018) -
Lamp2 inhibits epithelial-mesenchymal transition by suppressing Snail expression in HCC
por: Zheng, Hao, et al.
Publicado: (2018) -
Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo
por: Lu, Xiangdong, et al.
Publicado: (2016) -
MiR-363 inhibits cisplatin chemoresistance of epithelial ovarian cancer by regulating snail-induced epithelial-mesenchymal transition
por: Cao, Lanqin, et al.
Publicado: (2018) -
Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis
por: Zhou, Wencheng, et al.
Publicado: (2016)