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Evidence update for the treatment of anaphylaxis
The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guide...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/north-Holland Biomedical Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139870/ https://www.ncbi.nlm.nih.gov/pubmed/33895231 http://dx.doi.org/10.1016/j.resuscitation.2021.04.010 |
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author | Dodd, Amy Hughes, Anna Sargant, Nicholas Whyte, Andrew F. Soar, Jasmeet Turner, Paul J. |
author_facet | Dodd, Amy Hughes, Anna Sargant, Nicholas Whyte, Andrew F. Soar, Jasmeet Turner, Paul J. |
author_sort | Dodd, Amy |
collection | PubMed |
description | The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline. These include: emphasis on repeating intramuscular adrenaline doses after 5 min if symptoms of anaphylaxis do not resolve; corticosteroids (e.g. hydrocortisone) no longer being routinely recommended for the emergency treatment of anaphylaxis; interventions for reactions which are refractory to initial treatment with adrenaline; a recommendation against the use of antihistamines for the acute management of anaphylaxis; and guidance relating to the duration of observation following anaphylaxis, and timing of discharge. |
format | Online Article Text |
id | pubmed-8139870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier/north-Holland Biomedical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-81398702021-06-01 Evidence update for the treatment of anaphylaxis Dodd, Amy Hughes, Anna Sargant, Nicholas Whyte, Andrew F. Soar, Jasmeet Turner, Paul J. Resuscitation Review The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline. These include: emphasis on repeating intramuscular adrenaline doses after 5 min if symptoms of anaphylaxis do not resolve; corticosteroids (e.g. hydrocortisone) no longer being routinely recommended for the emergency treatment of anaphylaxis; interventions for reactions which are refractory to initial treatment with adrenaline; a recommendation against the use of antihistamines for the acute management of anaphylaxis; and guidance relating to the duration of observation following anaphylaxis, and timing of discharge. Elsevier/north-Holland Biomedical Press 2021-06 /pmc/articles/PMC8139870/ /pubmed/33895231 http://dx.doi.org/10.1016/j.resuscitation.2021.04.010 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dodd, Amy Hughes, Anna Sargant, Nicholas Whyte, Andrew F. Soar, Jasmeet Turner, Paul J. Evidence update for the treatment of anaphylaxis |
title | Evidence update for the treatment of anaphylaxis |
title_full | Evidence update for the treatment of anaphylaxis |
title_fullStr | Evidence update for the treatment of anaphylaxis |
title_full_unstemmed | Evidence update for the treatment of anaphylaxis |
title_short | Evidence update for the treatment of anaphylaxis |
title_sort | evidence update for the treatment of anaphylaxis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139870/ https://www.ncbi.nlm.nih.gov/pubmed/33895231 http://dx.doi.org/10.1016/j.resuscitation.2021.04.010 |
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