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Budding yeast Rad51: a paradigm for how phosphorylation and intrinsic structural disorder regulate homologous recombination and protein homeostasis

The RecA-family recombinase Rad51 is the central player in homologous recombination (HR), the faithful pathway for repairing DNA double-strand breaks (DSBs) during both mitosis and meiosis. The behavior of Rad51 protein in vivo is fine-tuned via posttranslational modifications conducted by multiple...

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Detalles Bibliográficos
Autores principales: Woo, Tai-Ting, Chuang, Chi-Ning, Wang, Ting-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139929/
https://www.ncbi.nlm.nih.gov/pubmed/33433732
http://dx.doi.org/10.1007/s00294-020-01151-2