Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer

Mucin 5AC (MUC5AC) is a secreted gel-forming mucin expressed by several epithelia. In the colon, MUC5AC is expressed in scattered normal epithelial cells but can be abundant in colorectal cancers. To clarify the relationship of MUC5AC expression with parameters of tumor aggressiveness and mismatch r...

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Detalles Bibliográficos
Autores principales: Rico, Sebastian Dwertmann, Höflmayer, Doris, Büscheck, Franziska, Dum, David, Luebke, Andreas M., Kluth, Martina, Hube-Magg, Claudia, Hinsch, Andrea, Möller-Koop, Christina, Perez, Daniel, Izbicki, Jakob R., Neipp, Michael, Mofid, Hamid, Lárusson, Hannes, Daniels, Thies, Isbert, Christoph, Coerper, Stephan, Ditterich, Daniel, Rupprecht, Holger, Goetz, Albert, Fraune, Christoph, Möller, Katharina, Menz, Anne, Bernreuther, Christian, Clauditz, Till S., Sauter, Guido, Uhlig, Ria, Wilczak, Waldemar, Simon, Ronald, Steurer, Stefan, Lebok, Patrick, Burandt, Eike, Krech, Till, Marx, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139930/
https://www.ncbi.nlm.nih.gov/pubmed/33373033
http://dx.doi.org/10.1007/s00795-020-00274-2

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