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Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells

The developmental origins of mesenchymal progenitor cells (MPCs) and molecular machineries regulating their fate and differentiation are far from defined owing to their complexity. Osteoblasts and adipocytes are descended from common MPCs. Their fates are collectively determined by an orchestra of p...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Beilter, Allyson, Xu, Zhaohui, Gao, Ruli, Xiong, Shunbin, Paulucci-Holthauzen, Adriana, Lozano, Guillermina, de Crombrugghe, Benoit, Gorlick, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139956/
https://www.ncbi.nlm.nih.gov/pubmed/34021120
http://dx.doi.org/10.1038/s41419-021-03758-w

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