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Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells
The developmental origins of mesenchymal progenitor cells (MPCs) and molecular machineries regulating their fate and differentiation are far from defined owing to their complexity. Osteoblasts and adipocytes are descended from common MPCs. Their fates are collectively determined by an orchestra of p...
Autores principales: | Zhou, Xin, Beilter, Allyson, Xu, Zhaohui, Gao, Ruli, Xiong, Shunbin, Paulucci-Holthauzen, Adriana, Lozano, Guillermina, de Crombrugghe, Benoit, Gorlick, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139956/ https://www.ncbi.nlm.nih.gov/pubmed/34021120 http://dx.doi.org/10.1038/s41419-021-03758-w |
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