IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) has a poor prognosis compared to other breast cancer subtypes. Although epidermal growth factor receptor (EGFR) is overexpressed in TNBC, clinical trials with EGFR inhibitors including tyrosine kinase inhibitors (EGFR-TKI) in TNBC have heretofore been unsuccessfu...

Descripción completa

Detalles Bibliográficos
Autores principales: Itoh, Takumi, Hatano, Ryo, Horimoto, Yoshiya, Yamada, Taketo, Song, Dan, Otsuka, Haruna, Shirakawa, Yuki, Mastuoka, Shuji, Iwao, Noriaki, Aune, Thomas M., Dang, Nam H., Kaneko, Yutaro, Okumura, Ko, Morimoto, Chikao, Ohnuma, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139965/
https://www.ncbi.nlm.nih.gov/pubmed/34021125
http://dx.doi.org/10.1038/s41419-021-03787-5

Ejemplares similares

Ejemplares similares