Active suppression prevents the return of threat memory in humans

Unbidden distressing memories inflict serious damage on mental health. Extant research highlights the importance of associative learning in modulating aversive memory. We report that conscious active suppression eliminates learned fear responses independent of memory triggers and is related to indiv...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Zhu, Zijian, Hu, Jingchu, Schiller, Daniela, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139982/
https://www.ncbi.nlm.nih.gov/pubmed/34021234
http://dx.doi.org/10.1038/s42003-021-02120-2
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author Wang, Ye
Zhu, Zijian
Hu, Jingchu
Schiller, Daniela
Li, Jian
author_facet Wang, Ye
Zhu, Zijian
Hu, Jingchu
Schiller, Daniela
Li, Jian
author_sort Wang, Ye
collection PubMed
description Unbidden distressing memories inflict serious damage on mental health. Extant research highlights the importance of associative learning in modulating aversive memory. We report that conscious active suppression eliminates learned fear responses independent of memory triggers and is related to individual difference in thought control ability; in contrast, thought diversion only reduces cue-specific fear response. These results suggest potential avenues for treatment of persistent maladaptive memories by engaging declarative mnemonic control mechanisms.
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spelling pubmed-81399822021-06-03 Active suppression prevents the return of threat memory in humans Wang, Ye Zhu, Zijian Hu, Jingchu Schiller, Daniela Li, Jian Commun Biol Article Unbidden distressing memories inflict serious damage on mental health. Extant research highlights the importance of associative learning in modulating aversive memory. We report that conscious active suppression eliminates learned fear responses independent of memory triggers and is related to individual difference in thought control ability; in contrast, thought diversion only reduces cue-specific fear response. These results suggest potential avenues for treatment of persistent maladaptive memories by engaging declarative mnemonic control mechanisms. Nature Publishing Group UK 2021-05-21 /pmc/articles/PMC8139982/ /pubmed/34021234 http://dx.doi.org/10.1038/s42003-021-02120-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wang, Ye
Zhu, Zijian
Hu, Jingchu
Schiller, Daniela
Li, Jian
Active suppression prevents the return of threat memory in humans
title Active suppression prevents the return of threat memory in humans
title_full Active suppression prevents the return of threat memory in humans
title_fullStr Active suppression prevents the return of threat memory in humans
title_full_unstemmed Active suppression prevents the return of threat memory in humans
title_short Active suppression prevents the return of threat memory in humans
title_sort active suppression prevents the return of threat memory in humans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139982/
https://www.ncbi.nlm.nih.gov/pubmed/34021234
http://dx.doi.org/10.1038/s42003-021-02120-2
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