Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury

Accumulation of vascular smooth muscle cells (VSMCs) is a hallmark of multiple vascular pathologies, including following neointimal formation after injury and atherosclerosis. However, human VSMCs in advanced atherosclerotic lesions show reduced cell proliferation, extensive and persistent DNA damag...

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Detalles Bibliográficos
Autores principales: Uryga, Anna K., Grootaert, Mandy O. J., Garrido, Abel M., Oc, Sebnem, Foote, Kirsty, Chappell, Joel, Finigan, Alison, Rossiello, Francesca, d’Adda di Fagagna, Fabrizio, Aravani, Dimitra, Jorgensen, Helle F., Bennett, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140103/
https://www.ncbi.nlm.nih.gov/pubmed/34021256
http://dx.doi.org/10.1038/s42003-021-02123-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140103/
https://www.ncbi.nlm.nih.gov/pubmed/34021256
http://dx.doi.org/10.1038/s42003-021-02123-z

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