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Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury
Accumulation of vascular smooth muscle cells (VSMCs) is a hallmark of multiple vascular pathologies, including following neointimal formation after injury and atherosclerosis. However, human VSMCs in advanced atherosclerotic lesions show reduced cell proliferation, extensive and persistent DNA damag...
Autores principales: | Uryga, Anna K., Grootaert, Mandy O. J., Garrido, Abel M., Oc, Sebnem, Foote, Kirsty, Chappell, Joel, Finigan, Alison, Rossiello, Francesca, d’Adda di Fagagna, Fabrizio, Aravani, Dimitra, Jorgensen, Helle F., Bennett, Martin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140103/ https://www.ncbi.nlm.nih.gov/pubmed/34021256 http://dx.doi.org/10.1038/s42003-021-02123-z |
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