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A novel RANKL‐targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species
BACKGROUND AND PURPOSE: Osteoporosis is characterized by excessive bone resorption due to enhanced osteoclast activation. Stimulation of nuclear factor of activated T cells 1 (NFATc1) and accumulation of reactive oxygen species (ROS) are important mechanisms underlying osteoclastogenesis. Robinin (R...
Autores principales: | Hong, Guoju, Chen, Zhenqiu, Han, Xiaorui, Zhou, Lin, Pang, Fengxiang, Wu, Rishana, Shen, Yingshan, He, Xiaoming, Hong, Zhinan, Li, Ziqi, He, Wei, Wei, Qiushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140192/ https://www.ncbi.nlm.nih.gov/pubmed/34047464 http://dx.doi.org/10.1002/ctm2.392 |
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