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Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors
Various nanoparticles have been developed for bio-applications. However, nanocomposites particles, (NCPs) with effective and ability to sensing cholesterol, are still needed. Herein, we present new cholesterol and pH-responsive NCPs as sensor particles to promote sensitivity. The traditional method...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140320/ http://dx.doi.org/10.1007/s10854-021-06102-2 |
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author | Abdul-Hamead, Alaa A. Othman, Farhad M. Fakhri, Makram A. |
author_facet | Abdul-Hamead, Alaa A. Othman, Farhad M. Fakhri, Makram A. |
author_sort | Abdul-Hamead, Alaa A. |
collection | PubMed |
description | Various nanoparticles have been developed for bio-applications. However, nanocomposites particles, (NCPs) with effective and ability to sensing cholesterol, are still needed. Herein, we present new cholesterol and pH-responsive NCPs as sensor particles to promote sensitivity. The traditional method of mixing and grinding was used to fabricate the oxides of magnesium and manganese MgO–MnO(2) NCPs with different mixing ratios. Structural properties, detection of cholesterol, and pH sensitivity were examined. Results propped the high efficiency of MgO–MnO(2) NCPs compared with individual oxides (MgO and MnO(2)), low response time, while the analytical results confirmed the homogeneous structure of MgO–MnO(2) NCPs. Particle size distribution results for NCPs were within 16.4 to 100 nm, which makes it promising in medical and bio-applications. |
format | Online Article Text |
id | pubmed-8140320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-81403202021-05-24 Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors Abdul-Hamead, Alaa A. Othman, Farhad M. Fakhri, Makram A. J Mater Sci: Mater Electron Article Various nanoparticles have been developed for bio-applications. However, nanocomposites particles, (NCPs) with effective and ability to sensing cholesterol, are still needed. Herein, we present new cholesterol and pH-responsive NCPs as sensor particles to promote sensitivity. The traditional method of mixing and grinding was used to fabricate the oxides of magnesium and manganese MgO–MnO(2) NCPs with different mixing ratios. Structural properties, detection of cholesterol, and pH sensitivity were examined. Results propped the high efficiency of MgO–MnO(2) NCPs compared with individual oxides (MgO and MnO(2)), low response time, while the analytical results confirmed the homogeneous structure of MgO–MnO(2) NCPs. Particle size distribution results for NCPs were within 16.4 to 100 nm, which makes it promising in medical and bio-applications. Springer US 2021-05-22 2021 /pmc/articles/PMC8140320/ http://dx.doi.org/10.1007/s10854-021-06102-2 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Abdul-Hamead, Alaa A. Othman, Farhad M. Fakhri, Makram A. Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title | Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title_full | Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title_fullStr | Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title_full_unstemmed | Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title_short | Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors |
title_sort | preparation of mgo–mno(2) nanocomposite particles for cholesterol sensors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140320/ http://dx.doi.org/10.1007/s10854-021-06102-2 |
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