Cargando…

LncRNA GAS5 modulates the progression of non-small cell lung cancer through repressing miR-221-3p and up-regulating IRF2

BACKGROUND: Long non-coding RNA growth arrest specific 5 (GAS5) is a regulator in non-small cell lung cancer (NSCLC) progression. Nonetheless, the mechanism by which GAS5 exerts its biological function in NSCLC cells remains unclear. METHODS: GAS5, miR-221-3p relative expression levels in NSCLC tiss...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Juan, Miao, Haiyan, Zhang, Haiyun, Ren, Jingjing, Qu, Shengyan, Da, Jing, Xu, Feifan, Zhao, Huan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140465/ https://www.ncbi.nlm.nih.gov/pubmed/34022918 http://dx.doi.org/10.1186/s13000-021-01108-0

Ejemplares similares

LncRNA ENSMUST_147219 mediates the progression of ischemic acute kidney injury by targeting the miR-221-5p/IRF6 axis
por: Liu, Jing, et al.
Publicado: (2022)

miR-221/222 promote tumor growth and suppress apoptosis by targeting lncRNA GAS5 in breast cancer
por: Zong, Yuanyuan, et al.
Publicado: (2019)

Retraction: miR-221/222 promote tumor growth and suppress apoptosis by targeting lncRNA GAS5 in breast cancer
Publicado: (2021)

lncRNA GAS5 Reverses EMT and Tumor Stem Cell-Mediated Gemcitabine Resistance and Metastasis by Targeting miR-221/SOCS3 in Pancreatic Cancer
por: Liu, Bingyan, et al.
Publicado: (2018)

Downregulation of miR-221-3p by LncRNA TUG1 Promoting the Healing of Closed Tibial Fractures in Mice
por: Liu, Laiyou, et al.
Publicado: (2022)

Expression of lncRNA MIR222HG co-transcribed from the miR-221/222 gene promoter facilitates the development of castration-resistant prostate cancer
por: Sun, Tong, et al.
Publicado: (2018)

LncRNA GAS5 represses stemness and malignancy of gliomas via elevating the SPACA6-miR-125a/let-7e Axis
por: Wu, Shuang, et al.
Publicado: (2022)

LncRNA miR663AHG represses the development of colon cancer in a miR663a-dependent manner
por: Yuan, Hongfan, et al.
Publicado: (2023)

LncRNA HOXA11‐AS promotes hepatocellular carcinoma progression by repressing miR‐214‐3p
por: Zhan, Meixiao, et al.
Publicado: (2018)

lncRNA NR4A1AS Upregulates miR-221 Through Demethylation to Promote Cell Proliferation in Oral Squamous Cell Carcinoma
por: Yang, Liuqing, et al.
Publicado: (2020)

The lncRNA-GAS5/miR-221-3p/DKK2 Axis Modulates ABCB1-Mediated Adriamycin Resistance of Breast Cancer via the Wnt/β-Catenin Signaling Pathway
por: Chen, Zhaolin, et al.
Publicado: (2020)

lncRNA GAS5 Is Upregulated in Osteoporosis and Downregulates miR-21 to Promote Apoptosis of Osteoclasts
por: Cong, Chunlei, et al.
Publicado: (2020)

Knockdown of lncRNA TapSAKI alleviates LPS-induced injury in HK-2 cells through the miR-205/IRF3 pathway
por: Han, Xiaoning, et al.
Publicado: (2021)

Interplay of lncRNA H19/miR‐675 and lncRNA NEAT1/miR‐204 in breast cancer
por: Müller, Volkmar, et al.
Publicado: (2019)

PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
por: Hanna, Jason A., et al.
Publicado: (2018)

lncRNA LEF1-AS1 Promotes Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Regulating miR-221/PTEN Signaling
por: Xiang, Chen, et al.
Publicado: (2020)

LncRNA GAS5 Suppresses Colorectal Cancer Progress by Target miR-21/LIFR Axis
por: Xie, Juan, et al.
Publicado: (2022)

Transcriptional repression of lncRNA and miRNA subsets mediated by LRF during erythropoiesis
por: Athanasopoulou, Katerina, et al.
Publicado: (2023)

LncRNA CASC15 Functions As An Unfavorable Predictor Of Ovarian Cancer Prognosis And Inhibits Tumor Progression Through Regulation Of miR-221/ARID1A Axis
por: Shi, Yin, et al.
Publicado: (2019)

lncRNA SNHG16 promotes the occurrence of osteoarthritis by sponging miR-373-3p
por: Fan, Haiyan, et al.
Publicado: (2021)

LncRNA-GAS5 induces PTEN expression through inhibiting miR-103 in endometrial cancer cells
por: Guo, Chen, et al.
Publicado: (2015)

LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway
por: Xie, Rong, et al.
Publicado: (2023)

LncRNA FLAIL affects alternative splicing and represses flowering in Arabidopsis
por: Jin, Yu, et al.
Publicado: (2023)

Proximity-dependent recruitment of Polycomb repressive complexes by the lncRNA Airn
por: Braceros, Aki K., et al.
Publicado: (2023)

The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia
por: Li, Kaitao, et al.
Publicado: (2023)

LncRNA miR143HG Up-Regulates p53 In Endometrial Carcinoma By Sponging miR-125a
por: Shi, Fan, et al.
Publicado: (2019)

The Reciprocal Interaction Between LncRNA CCAT1 and miR-375-3p Contribute to the Downregulation of IRF5 Gene Expression by Solasonine in HepG2 Human Hepatocellular Carcinoma Cells
por: Liu, Zheng, et al.
Publicado: (2019)

Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis
por: Xiao, Xi, et al.
Publicado: (2021)

Plasma Levels of microRNA-221 (miR-221) are Increased in Patients with Acute Pulmonary Embolism
por: Liu, Tingwei, et al.
Publicado: (2018)

miR-124-3p sabotages lncRNA MALAT1 stability to repress chondrocyte pyroptosis and relieve cartilage injury in osteoarthritis
por: Rozi, Rigbat, et al.
Publicado: (2022)

LncRNA GAS8‐AS1 downregulates lncRNA NEAT1 to inhibit glioblastoma cell proliferation
por: Wu, Xiaoming, et al.
Publicado: (2021)

Downregulated lncRNA GAS5 and Upregulated miR-21 Lead to Epithelial–Mesenchymal Transition and Lung Metastasis of Osteosarcomas
por: Wang, Ying, et al.
Publicado: (2021)

MiR-665 Regulates Vascular Smooth Muscle Cell Senescence by Interacting With LncRNA GAS5/SDC1
por: Chen, Tianbin, et al.
Publicado: (2021)

LncRNA GAS5 suppresses ovarian cancer progression by targeting the miR-96-5p/PTEN axis
por: Dong, Qian, et al.
Publicado: (2021)

A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation
por: Xu, Huaming, et al.
Publicado: (2023)

LncRNA PVT1 influences breast cancer cells glycolysis through sponging miR-145-5p
por: Qu, Huan, et al.
Publicado: (2023)

Association of LncRNA‐GAS5 gene polymorphisms and PBMC LncRNA‐GAS5 level with risk of systemic lupus erythematosus in Chinese population
por: Liu, Chun‐Hong, et al.
Publicado: (2021)

lncRNA XIST inhibition promotes M2 polarization of microglial and aggravates the spinal cord injury via regulating miR-124–3p / IRF1 axis
por: Yang, Jin, et al.
Publicado: (2023)

LncRNA GAS6‐AS2 promotes bladder cancer proliferation and metastasis via GAS6‐AS2/miR‐298/CDK9 axis
por: Rui, Xin, et al.
Publicado: (2018)

Expression and prognostic significance of miR-375 and miR-221 in liver cancer
por: Xie, Dafei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r0ijnfuo9uc7mte7oassiqrr62