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Repurposing beta-3 adrenergic receptor agonists for Alzheimer’s disease: beneficial effects in a mouse model

BACKGROUND: Old age, the most important risk factor for Alzheimer’s disease (AD), is associated with thermoregulatory deficits. Brown adipose tissue (BAT) is the main thermogenic driver in mammals and its stimulation, through β3 adrenergic receptor (β3AR) agonists or cold acclimation, counteracts me...

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Detalles Bibliográficos
Autores principales:	Tournissac, Marine, Vu, Tra-My, Vrabic, Nika, Hozer, Clara, Tremblay, Cyntia, Mélançon, Koralie, Planel, Emmanuel, Pifferi, Fabien, Calon, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140479/ https://www.ncbi.nlm.nih.gov/pubmed/34020681 http://dx.doi.org/10.1186/s13195-021-00842-3

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