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Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling

Testosterone (T) reduces male fat mass, but the underlying mechanisms remain elusive, limiting its clinical relevance in hypogonadism-associated obesity. Here, we subjected chemically castrated high-fat diet–induced adult obese male mice to supplementation with T or the nonaromatizable androgen dihy...

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Detalles Bibliográficos
Autores principales: Kim, Na Ri, David, Karel, Corbeels, Katrien, Khalil, Rougin, Antonio, Leen, Schollaert, Dieter, Deboel, Ludo, Ohlsson, Claes, Gustafsson, Jan-Åke, Vangoitsenhoven, Roman, Van der Schueren, Bart, Decallonne, Brigitte, Claessens, Frank, Vanderschueren, Dirk, Dubois, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140602/
https://www.ncbi.nlm.nih.gov/pubmed/33674833
http://dx.doi.org/10.1210/endocr/bqab045