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Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling
Testosterone (T) reduces male fat mass, but the underlying mechanisms remain elusive, limiting its clinical relevance in hypogonadism-associated obesity. Here, we subjected chemically castrated high-fat diet–induced adult obese male mice to supplementation with T or the nonaromatizable androgen dihy...
Autores principales: | Kim, Na Ri, David, Karel, Corbeels, Katrien, Khalil, Rougin, Antonio, Leen, Schollaert, Dieter, Deboel, Ludo, Ohlsson, Claes, Gustafsson, Jan-Åke, Vangoitsenhoven, Roman, Van der Schueren, Bart, Decallonne, Brigitte, Claessens, Frank, Vanderschueren, Dirk, Dubois, Vanessa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140602/ https://www.ncbi.nlm.nih.gov/pubmed/33674833 http://dx.doi.org/10.1210/endocr/bqab045 |
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