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Integrating Clinical and Polygenic Factors to Predict Breast Cancer Risk in Women Undergoing Genetic Testing

PURPOSE: Screening and prevention decisions for women at increased risk of developing breast cancer depend on genetic and clinical factors to estimate risk and select appropriate interventions. Integration of polygenic risk into clinical breast cancer risk estimators can improve discrimination. Howe...

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Detalles Bibliográficos
Autores principales: Hughes, Elisha, Tshiaba, Placede, Wagner, Susanne, Judkins, Thaddeus, Rosenthal, Eric, Roa, Benjamin, Gallagher, Shannon, Meek, Stephanie, Dalton, Kathryn, Hedegard, Wade, Adami, Carol A., Grear, Danna F., Domchek, Susan M., Garber, Judy, Lancaster, Johnathan M., Weitzel, Jeffrey N., Kurian, Allison W., Lanchbury, Jerry S., Gutin, Alexander, Robson, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140787/
https://www.ncbi.nlm.nih.gov/pubmed/34036224
http://dx.doi.org/10.1200/PO.20.00246

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