Cargando…
Integrating Clinical and Polygenic Factors to Predict Breast Cancer Risk in Women Undergoing Genetic Testing
PURPOSE: Screening and prevention decisions for women at increased risk of developing breast cancer depend on genetic and clinical factors to estimate risk and select appropriate interventions. Integration of polygenic risk into clinical breast cancer risk estimators can improve discrimination. Howe...
Autores principales: | Hughes, Elisha, Tshiaba, Placede, Wagner, Susanne, Judkins, Thaddeus, Rosenthal, Eric, Roa, Benjamin, Gallagher, Shannon, Meek, Stephanie, Dalton, Kathryn, Hedegard, Wade, Adami, Carol A., Grear, Danna F., Domchek, Susan M., Garber, Judy, Lancaster, Johnathan M., Weitzel, Jeffrey N., Kurian, Allison W., Lanchbury, Jerry S., Gutin, Alexander, Robson, Mark E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140787/ https://www.ncbi.nlm.nih.gov/pubmed/34036224 http://dx.doi.org/10.1200/PO.20.00246 |
Ejemplares similares
-
Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer Risk
por: Hughes, Elisha, et al.
Publicado: (2020) -
Association of a Polygenic Risk Score With Breast Cancer Among Women Carriers of High- and Moderate-Risk Breast Cancer Genes
por: Gallagher, Shannon, et al.
Publicado: (2020) -
Comprehensive Breast Cancer Risk Assessment for CHEK2 and ATM Pathogenic Variant Carriers Incorporating a Polygenic Risk Score and the Tyrer-Cuzick Model
por: Gallagher, Shannon, et al.
Publicado: (2021) -
Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition
por: Hughes, Elisha, et al.
Publicado: (2022) -
Integration of a Cross-Ancestry Polygenic Model With Clinical Risk Factors Improves Breast Cancer Risk Stratification
por: Tshiaba, Placede T., et al.
Publicado: (2023)