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Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta

Gentiopicroside (GPS), a main active secoiridoid glucoside derived from the roots of perennial herbs in the Gentianaceae family, has antispasmodic and relaxant effects. However, the vasorelaxant effects of GPS on aortic rings and the molecular mechanisms involved in these effects are not yet clear....

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Detalles Bibliográficos
Autores principales:	Xing, Shangping, Nong, Feifei, Qin, Jialiang, Huang, Huicai, Zhan, Ruoting, Chen, Weiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140822/ https://www.ncbi.nlm.nih.gov/pubmed/34095301 http://dx.doi.org/10.1155/2021/5565748

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