Cargando…

Plasma Pharmacokinetic Parameters of Dexamethasone Following Administration of a Dexamethasone Intracanalicular Insert in Healthy Adults

PURPOSE: Intracanalicular dexamethasone insert is a resorbable sustained-release polyethylene glycol-based hydrogel insert delivering a 0.4 mg tapered dose of dexamethasone for up to 30 days to the ocular surface. It is FDA-approved for treating inflammation and pain after ocular surgery. It has als...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blizzard, Charles, McLaurin, Eugene B, Driscoll, Arthur, Silva, Fabiana Q, Vantipalli, Srilatha, Metzinger, Jamie Lynne, Goldstein, Michael H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140928/ https://www.ncbi.nlm.nih.gov/pubmed/34040341 http://dx.doi.org/10.2147/OPTH.S307194

Ejemplares similares

Early Real-World Physician Experience with an Intracanalicular Dexamethasone Insert
por: Matossian, Cynthia, et al.
Publicado: (2022)

Evaluating the patient experience after implantation of a 0.4 mg sustained release dexamethasone intracanalicular insert (Dextenza™): results of a qualitative survey
por: Gira, Joseph P, et al.
Publicado: (2017)

Pharmacokinetic Studies of Sustained-Release Depot of Dexamethasone in Beagle Dogs
por: Blizzard, Charles, et al.
Publicado: (2016)

Dexamethasone Intracanalicular Insert: A Review in Treating Post-Surgical Ocular Pain and Inflammation
por: Lee, Arnold, et al.
Publicado: (2020)

Intracanalicular Dexamethasone Insert or Topical Prednisolone Following iStent and Hydrus Surgery for Glaucoma
por: Jackson, Kevin J., et al.
Publicado: (2022)

Correction to: Dexamethasone Intracanalicular Insert: A Review in Treating Post-Surgical Ocular Pain and Inflammation
por: Lee, Arnold, et al.
Publicado: (2020)

Dexamethasone Sustained-Release Intracanalicular Insert for Control of Postoperative Inflammation After Pars Plana Vitrectomy
por: Suñer, Ivan J, et al.
Publicado: (2021)

Thermal Pulsation with or without Dexamethasone Intracanalicular Insert for Meibomian Gland Dysfunction: A Prospective, Masked Trial
por: Dierker, Damon S, et al.
Publicado: (2022)

Same-Day versus Next-Day Dexamethasone Intracanalicular Insert Administration for Inflammation and Pain Control Following Cataract Surgery: A Retrospective Analysis
por: Foster, Brian
Publicado: (2021)

Retrospective Study of a Sustained-Release Intracanalicular Dexamethasone Insert for Treatment of Ocular Inflammation After Cataract and Corneal Surgery
por: Fram, Nicole, et al.
Publicado: (2022)

Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
por: Brooks, Cassandra C, et al.
Publicado: (2020)

Prospective, Randomized, Fellow Eye-Controlled Study of Postoperative Pain and Inflammation Control with an Intracanalicular Dexamethasone 0.4 mg Ophthalmic Insert Following Small Incision Lenticule Extraction
por: Jee, Kathleen J, et al.
Publicado: (2022)

Evaluation of Same-Day versus Next-Day Implantation of Intracanalicular Dexamethasone for the Control of Postoperative Inflammation and Pain Following Cataract Surgery
por: Saenz, Bobby, et al.
Publicado: (2021)

A Randomized, Controlled, Prospective Study of the Effectiveness and Safety of an Intracanalicular Dexamethasone Ophthalmic Insert (0.4 Mg) for the Treatment of Post-Operative Inflammation in Patients Undergoing Refractive Lens Exchange (RLE)
por: Larsen, Jacob, et al.
Publicado: (2021)

Ocular benzalkonium chloride exposure: problems and solutions
por: Goldstein, Michael H., et al.
Publicado: (2021)

The role of dexamethasone in the modification of misonidazole pharmacokinetics.
por: Jones, D. H., et al.
Publicado: (1983)

A Randomized Fellow-Eye Clinical Trial to Evaluate Patient Preference for Dexamethasone Intracanalicular Insert or Topical Prednisolone Acetate for Control of Postoperative Symptoms Following Bilateral Femtosecond Laser in Site Keratomileusis (LASIK)
por: Greenwood, Michael D, et al.
Publicado: (2020)

The DEPOT Study (Dry Eye Prescription Options for Therapy): Assessing the Efficacy and Safety of OTX-DED (Dexamethasone Ophthalmic Insert 0.3 mg) for Intracanalicular Use Compared with Loteprednol Suspension for the Treatment of Episodic Dry Eye
por: Hovanesian, John A, et al.
Publicado: (2022)

Intracanalicular Osteochondroma in the Lumbar Spine
por: Shigekiyo, Shota, et al.
Publicado: (2019)

Intracanalicular meningioma: diagnostic by immunohistochemistry
por: Borin, Andrei, et al.
Publicado: (2015)

A Randomized, Prospective, Observer-Masked Study Comparing Dropless Treatment Regimen Using Intracanalicular Dexamethasone Insert, Intracameral Ketorolac, and Intracameral Moxifloxacin versus Conventional Topical Therapy to Control Postoperative Pain and Inflammation in Cataract Surgery
por: Donnenfeld, Eric D, et al.
Publicado: (2023)

Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery
por: Kicková, Eva, et al.
Publicado: (2021)

Submucosal administration of dexamethasone for dental implant surgery
por: Flanagan, Dennis
Publicado: (2022)

Dexamethason
por: de Graaf, Linda, et al.
Publicado: (2020)

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers
por: Jang, Kyungho, et al.
Publicado: (2017)

Persistent Severe Hiccups After Dexamethasone Intravenous Administration
por: Sugandhavesa, Nantawit, et al.
Publicado: (2019)

Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium
por: Crisafulli, Umberto, et al.
Publicado: (2018)

Dexamethasone and Dexamethasone Phosphate: Effect on DMPC Membrane Models
por: Cámara, Candelaria Ines, et al.
Publicado: (2023)

In vivo observation of intracanalicular changes in association with blinking
por: Singh, Swati, et al.
Publicado: (2018)

Dexamethasone to the rescue
por: Moon, Chang
Publicado: (2020)

Dexamethasone for pulpitis
por: Emanuel, R.
Publicado: (2020)

Pharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbits
por: Zhang, Linhua, et al.
Publicado: (2009)

Comparison of the Pharmacokinetic Properties of Triamcinolone and Dexamethasone for Local Therapy of the Inner Ear
por: Salt, Alec Nicholas, et al.
Publicado: (2019)

Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women
por: Krzyzanski, Wojciech, et al.
Publicado: (2021)

Effect of Dexamethasone on Abiraterone Pharmacokinetics in Mice: Determined by LC/MS Analysis
por: Deb, Subrata, et al.
Publicado: (2023)

Are the immuno-stimulatory properties of Lenalidomide extinguished by co-administration of Dexamethasone?
por: Hsu, Andy, et al.
Publicado: (2012)

Effects of chronic dexamethasone administration on hyperglycemia and insulin release in goats
por: Niu, Liqiong, et al.
Publicado: (2018)

Plasma concentration of metformin and dexamethasone after administration through Osseogate
por: Kim, Hong-Kyun, et al.
Publicado: (2017)

The Effect of the Timing of Dexamethasone Administration in Patients with COVID-19 Pneumonia
por: Lee, Hyun Woo, et al.
Publicado: (2021)

Modified insertion technique for a sustained-release dexamethasone intravitreal implant (Ozurdex®)
por: Lee, Daniel H., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n7l5uij388ia6uuj8psp2qdhve