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MiR-21-5p in Macrophage-Derived Exosomes Targets Smad7 to Promote Epithelial Mesenchymal Transition of Airway Epithelial Cells

BACKGROUND: Asthma is usually associated with airway inflammation and airway remodeling. Epithelial mesenchymal transition (EMT) often occurs in airway remodeling. The purpose of this study is to identify the effect of miR-21-5p and Smad7 signaling pathway in macrophage-derived exosomes on EMT of ai...

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Detalles Bibliográficos
Autores principales:	Li, Xiang, Yang, Nan, Cheng, Qi, Zhang, Han, Liu, Fen, Shang, Yunxiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140948/ https://www.ncbi.nlm.nih.gov/pubmed/34040396 http://dx.doi.org/10.2147/JAA.S307165

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