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Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort

Hyperactivity is one of the three core symptoms in children with attention deficit hyperactivity disorder (ADHD). Diagnosing ADHD typically involves self-report, third party report and observations. Objective activity data can make a valuable contribution to the diagnostic process. Small actigraphy...

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Autores principales: Brandt, Valerie, Patalay, Praveetha, Kerner auch Koerner, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140967/
https://www.ncbi.nlm.nih.gov/pubmed/32506264
http://dx.doi.org/10.1007/s00787-020-01566-9
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author Brandt, Valerie
Patalay, Praveetha
Kerner auch Koerner, Julia
author_facet Brandt, Valerie
Patalay, Praveetha
Kerner auch Koerner, Julia
author_sort Brandt, Valerie
collection PubMed
description Hyperactivity is one of the three core symptoms in children with attention deficit hyperactivity disorder (ADHD). Diagnosing ADHD typically involves self-report, third party report and observations. Objective activity data can make a valuable contribution to the diagnostic process. Small actigraphy studies in clinical samples have shown that children with ADHD move more than children without ADHD. However, differences in physical activity between children with and without ADHD have not been assessed in large community samples or longitudinally. This study used data from the Millennium Cohort Study to test whether symptoms of ADHD (parent-rating Strengths and Difficulties Questionnaire) and ADHD diagnosis at age 14 (reported by parents) could be predicted from objective activity data (measured with actigraphs) at age 7 in N = 6675 children (final N = 5251). Regressions showed that less sedentary behavior at age 7 predicted more ADHD symptoms at age 14 (β =  − 0.002, CI  − 0.004 to  − 0.001). The result remained significant when controlled for ADHD symptoms at age 7, sex, BMI, month of birth, SES and ethnicity (β  =  − 0.001, CI  − 0.003 to  − 0.0003). ADHD diagnosis at age 14 was also significantly predicted by less sedentary behavior at age 7 (β  =  − 0.008). Our findings show that symptoms of ADHD can be predicted by objective activity data 5 years in advance and suggest that actigraphy could be a useful instrument aiding an ADHD diagnosis. Interestingly, the results indicate that the key difference between children with and without ADHD lies in reduced sedentary activity, i.e., times of rest. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00787-020-01566-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-81409672021-06-03 Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort Brandt, Valerie Patalay, Praveetha Kerner auch Koerner, Julia Eur Child Adolesc Psychiatry Original Contribution Hyperactivity is one of the three core symptoms in children with attention deficit hyperactivity disorder (ADHD). Diagnosing ADHD typically involves self-report, third party report and observations. Objective activity data can make a valuable contribution to the diagnostic process. Small actigraphy studies in clinical samples have shown that children with ADHD move more than children without ADHD. However, differences in physical activity between children with and without ADHD have not been assessed in large community samples or longitudinally. This study used data from the Millennium Cohort Study to test whether symptoms of ADHD (parent-rating Strengths and Difficulties Questionnaire) and ADHD diagnosis at age 14 (reported by parents) could be predicted from objective activity data (measured with actigraphs) at age 7 in N = 6675 children (final N = 5251). Regressions showed that less sedentary behavior at age 7 predicted more ADHD symptoms at age 14 (β =  − 0.002, CI  − 0.004 to  − 0.001). The result remained significant when controlled for ADHD symptoms at age 7, sex, BMI, month of birth, SES and ethnicity (β  =  − 0.001, CI  − 0.003 to  − 0.0003). ADHD diagnosis at age 14 was also significantly predicted by less sedentary behavior at age 7 (β  =  − 0.008). Our findings show that symptoms of ADHD can be predicted by objective activity data 5 years in advance and suggest that actigraphy could be a useful instrument aiding an ADHD diagnosis. Interestingly, the results indicate that the key difference between children with and without ADHD lies in reduced sedentary activity, i.e., times of rest. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00787-020-01566-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-06-06 2021 /pmc/articles/PMC8140967/ /pubmed/32506264 http://dx.doi.org/10.1007/s00787-020-01566-9 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Contribution
Brandt, Valerie
Patalay, Praveetha
Kerner auch Koerner, Julia
Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title_full Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title_fullStr Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title_full_unstemmed Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title_short Predicting ADHD symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large UK cohort
title_sort predicting adhd symptoms and diagnosis at age 14 from objective activity levels at age 7 in a large uk cohort
topic Original Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140967/
https://www.ncbi.nlm.nih.gov/pubmed/32506264
http://dx.doi.org/10.1007/s00787-020-01566-9
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