Cargando…
Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler
The SNF5 subunit of the SWI/SNF chromatin remodeling complex has been shown to act as a tumor suppressor through multiple mechanisms, including impairing the ability of the oncoprotein transcription factor MYC to bind chromatin. Beyond SNF5, however, it is unknown to what extent MYC can access addit...
Autores principales: | Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141032/ https://www.ncbi.nlm.nih.gov/pubmed/33931740 http://dx.doi.org/10.1038/s41388-021-01804-7 |
Ejemplares similares
-
Emerging Themes in Mechanisms of Tumorigenesis by SWI/SNF Subunit
Mutation
por: Jones, Cheyenne A., et al.
Publicado: (2022) -
Impact of WIN site inhibitor on the WDR5 interactome
por: Guarnaccia, Alissa D., et al.
Publicado: (2021) -
Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
por: Florian, Andrea C, et al.
Publicado: (2022) -
Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance
por: Thomas, Lance R., et al.
Publicado: (2019) -
The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells
por: Moe, Kylie C., et al.
Publicado: (2022)