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Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity
Ferroptosis, a form of regulated cell death triggered by lipid peroxidation, was recently identified as an important mechanism in radiotherapy (RT)-mediated tumor suppression and radioresistance, although the exact genetic contexts in which to target ferroptosis in RT remains to be defined. p53 is t...
Autores principales: | Lei, Guang, Zhang, Yilei, Hong, Ting, Zhang, Xudong, Liu, Xiaoguang, Mao, Chao, Yan, Yuelong, Koppula, Pranavi, Cheng, Weijie, Sood, Anil K., Liu, Jinsong, Gan, Boyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141034/ https://www.ncbi.nlm.nih.gov/pubmed/33927351 http://dx.doi.org/10.1038/s41388-021-01790-w |
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