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AIM2 nuclear exit and inflammasome activation in chronic obstructive pulmonary disease and response to cigarette smoke

INTRODUCTION: The role inflammasomes play in chronic obstructive pulmonary disease (COPD) is unclear. We hypothesised that the AIM2 inflammasome is activated in the airways of COPD patients, and in response to cigarette smoke. METHODS: Lung tissue, bronchoscopy-derived alveolar macrophages and bronc...

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Detalles Bibliográficos
Autores principales:	Tran, Hai B., Hamon, Rhys, Jersmann, Hubertus, Ween, Miranda P., Asare, Patrick, Haberberger, Rainer, Pant, Harshita, Hodge, Sandra J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141226/ https://www.ncbi.nlm.nih.gov/pubmed/34022905 http://dx.doi.org/10.1186/s12950-021-00286-4

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