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Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141307/ https://www.ncbi.nlm.nih.gov/pubmed/33340078 http://dx.doi.org/10.4317/medoral.24230 |
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author | Georgakopoulou, Eleni Loumou, Panagiota Grigoraki, Aikaterini Panagiotopoulos, Antonios |
author_facet | Georgakopoulou, Eleni Loumou, Panagiota Grigoraki, Aikaterini Panagiotopoulos, Antonios |
author_sort | Georgakopoulou, Eleni |
collection | PubMed |
description | BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemic agents, e.g. corticosteroids, have been used to treat inflammatory lip conditions. Topical tacrolimus has also been used in some inflammatory lip conditions. MATERIAL AND METHODS: We performed a retrospective clinical analysis of atopic cheilitis patients. RESULTS: Between 2015 and 2020, we addressed 7 (seven) patients with atopic dermatitis affecting only lips and were diagnosed as atopic-eczematous cheilitis. They were treated with 0.03 per cent topical tacrolimus ointment and responded completely. CONCLUSIONS: These cases represent an underreported atopy / eczema event;-few cases of atopic cheilitis without concomitant dermal lesions appear in the literature. We are also showing and discussing yet another application of tacrolimus in a local atopic form of inflammation affecting the lips. Key words:Atopy, cheilitis, tacrolimus. |
format | Online Article Text |
id | pubmed-8141307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81413072021-05-26 Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% Georgakopoulou, Eleni Loumou, Panagiota Grigoraki, Aikaterini Panagiotopoulos, Antonios Med Oral Patol Oral Cir Bucal Research BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemic agents, e.g. corticosteroids, have been used to treat inflammatory lip conditions. Topical tacrolimus has also been used in some inflammatory lip conditions. MATERIAL AND METHODS: We performed a retrospective clinical analysis of atopic cheilitis patients. RESULTS: Between 2015 and 2020, we addressed 7 (seven) patients with atopic dermatitis affecting only lips and were diagnosed as atopic-eczematous cheilitis. They were treated with 0.03 per cent topical tacrolimus ointment and responded completely. CONCLUSIONS: These cases represent an underreported atopy / eczema event;-few cases of atopic cheilitis without concomitant dermal lesions appear in the literature. We are also showing and discussing yet another application of tacrolimus in a local atopic form of inflammation affecting the lips. Key words:Atopy, cheilitis, tacrolimus. Medicina Oral S.L. 2021-05 2020-12-19 /pmc/articles/PMC8141307/ /pubmed/33340078 http://dx.doi.org/10.4317/medoral.24230 Text en Copyright: © 2021 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Georgakopoulou, Eleni Loumou, Panagiota Grigoraki, Aikaterini Panagiotopoulos, Antonios Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title | Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title_full | Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title_fullStr | Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title_full_unstemmed | Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title_short | Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
title_sort | isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141307/ https://www.ncbi.nlm.nih.gov/pubmed/33340078 http://dx.doi.org/10.4317/medoral.24230 |
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