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Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%

BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemi...

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Autores principales: Georgakopoulou, Eleni, Loumou, Panagiota, Grigoraki, Aikaterini, Panagiotopoulos, Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141307/
https://www.ncbi.nlm.nih.gov/pubmed/33340078
http://dx.doi.org/10.4317/medoral.24230
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author Georgakopoulou, Eleni
Loumou, Panagiota
Grigoraki, Aikaterini
Panagiotopoulos, Antonios
author_facet Georgakopoulou, Eleni
Loumou, Panagiota
Grigoraki, Aikaterini
Panagiotopoulos, Antonios
author_sort Georgakopoulou, Eleni
collection PubMed
description BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemic agents, e.g. corticosteroids, have been used to treat inflammatory lip conditions. Topical tacrolimus has also been used in some inflammatory lip conditions. MATERIAL AND METHODS: We performed a retrospective clinical analysis of atopic cheilitis patients. RESULTS: Between 2015 and 2020, we addressed 7 (seven) patients with atopic dermatitis affecting only lips and were diagnosed as atopic-eczematous cheilitis. They were treated with 0.03 per cent topical tacrolimus ointment and responded completely. CONCLUSIONS: These cases represent an underreported atopy / eczema event;-few cases of atopic cheilitis without concomitant dermal lesions appear in the literature. We are also showing and discussing yet another application of tacrolimus in a local atopic form of inflammation affecting the lips. Key words:Atopy, cheilitis, tacrolimus.
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spelling pubmed-81413072021-05-26 Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% Georgakopoulou, Eleni Loumou, Panagiota Grigoraki, Aikaterini Panagiotopoulos, Antonios Med Oral Patol Oral Cir Bucal Research BACKGROUND: Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemic agents, e.g. corticosteroids, have been used to treat inflammatory lip conditions. Topical tacrolimus has also been used in some inflammatory lip conditions. MATERIAL AND METHODS: We performed a retrospective clinical analysis of atopic cheilitis patients. RESULTS: Between 2015 and 2020, we addressed 7 (seven) patients with atopic dermatitis affecting only lips and were diagnosed as atopic-eczematous cheilitis. They were treated with 0.03 per cent topical tacrolimus ointment and responded completely. CONCLUSIONS: These cases represent an underreported atopy / eczema event;-few cases of atopic cheilitis without concomitant dermal lesions appear in the literature. We are also showing and discussing yet another application of tacrolimus in a local atopic form of inflammation affecting the lips. Key words:Atopy, cheilitis, tacrolimus. Medicina Oral S.L. 2021-05 2020-12-19 /pmc/articles/PMC8141307/ /pubmed/33340078 http://dx.doi.org/10.4317/medoral.24230 Text en Copyright: © 2021 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Georgakopoulou, Eleni
Loumou, Panagiota
Grigoraki, Aikaterini
Panagiotopoulos, Antonios
Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title_full Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title_fullStr Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title_full_unstemmed Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title_short Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
title_sort isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141307/
https://www.ncbi.nlm.nih.gov/pubmed/33340078
http://dx.doi.org/10.4317/medoral.24230
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