Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication

Viral proteins are known to be methylated by host protein arginine methyltransferases (PRMTs) necessary for the viral life cycle, but it remains unknown whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins are methylated. Herein, we show that PRMT1 methylates SARS-CoV-2 nucl...

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Detalles Bibliográficos
Autores principales: Cai, Ting, Yu, Zhenbao, Wang, Zhen, Liang, Chen, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141346/
https://www.ncbi.nlm.nih.gov/pubmed/34029587
http://dx.doi.org/10.1016/j.jbc.2021.100821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141346/
https://www.ncbi.nlm.nih.gov/pubmed/34029587
http://dx.doi.org/10.1016/j.jbc.2021.100821

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