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Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity

BACKGROUND: Dendritic cells (DCs) play a critical role in antitumor immunity, but the therapeutic efficacy of DC-mediated cancer vaccine remains low, partly due to unsustainable DC function in tumor antigen presentation. Thus, identifying drugs that could enhance DC-based antitumor immunity and unco...

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Detalles Bibliográficos
Autores principales:	Wang, Zining, Xu, Feifei, Hu, Jie, Zhang, Hongxia, Cui, Lei, Lu, Wenhua, He, Wenzhuo, Wang, Xiaojuan, Li, Mengyun, Zhang, Huanling, Xiong, Wenjing, Xie, Chunyuan, Liu, Yongxiang, Zhou, Penghui, Liu, Jinyun, Huang, Peng, Qin, Xiaofeng Frank, Xia, Xiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141455/ https://www.ncbi.nlm.nih.gov/pubmed/34016722 http://dx.doi.org/10.1136/jitc-2020-002155

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