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Krüppel like factor 10 prevents intervertebral disc degeneration via TGF-β signaling pathway both in vitro and in vivo
BACKGROUND: Krüppel like factor 10 (KLF10), which is also known as TGF-β Inducible Early Gene-1 (TIEG1), plays a crucial role in regulating cell proliferation, cell apoptosis and inflammatory reaction in human carcinoma cells. Moreover, KLF10 knockout in mice leads to severe defects associated with...
Autores principales: | Wu, Tongde, Li, Xinhua, Jia, Xuebing, Zhu, Ziqi, Lu, Jiawei, Feng, Hang, Shen, Beiduo, Guo, Kai, Li, Yuzhi, Wang, Qiang, Gao, Zhiqiang, Yu, Bin, Ba, Zhaoyu, Huang, Yufeng, Wu, Desheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141503/ https://www.ncbi.nlm.nih.gov/pubmed/34094855 http://dx.doi.org/10.1016/j.jot.2021.04.003 |
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