Identification of nucleic acid aptamers against lactate dehydrogenase via SELEX and high-throughput sequencing

Nucleic acid aptamers are small fragments of DNA or RNA molecules binding specifically to targets, which can be obtained through in vitro screening via systematic evolution of ligands by exponential enrichment (SELEX). Lactate dehydrogenase (LDH) is an important tumor marker, whose level in patients...

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Detalles Bibliográficos
Autores principales: Guo, Linghui, Song, Ying, Yuan, Yanwen, Chen, Jinlei, Liang, Haifeng, Guo, Fei, Yu, Zhi, Liang, Pei, Wang, Yapei, Wang, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141549/
https://www.ncbi.nlm.nih.gov/pubmed/34028561
http://dx.doi.org/10.1007/s00216-021-03397-2

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