Cargando…

Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients

AIM: Immunotherapy shows efficacy in only a subset of melanoma patients. Here, we intended to construct a risk score model to predict melanoma patients’ sensitivity to immunotherapy. METHODS: Integration analyses were performed on melanoma patients from high-dimensional public datasets. The CD8+ T c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Yuan, Zhu, Zheng, Lan, Ying, Duan, Saili, Zhu, Ziqing, Zhang, Xi, Li, Guoyin, Qu, Hui, Feng, Yanhui, Cai, Hui, Song, Zewen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141567/ https://www.ncbi.nlm.nih.gov/pubmed/34040608 http://dx.doi.org/10.3389/fimmu.2021.659444

Ejemplares similares

Core immune cell infiltration signatures identify molecular subtypes and promote precise checkpoint immunotherapy in cutaneous melanoma
por: Zhu, Zheng, et al.
Publicado: (2022)

Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig
por: Cai, DQ., et al.
Publicado: (2023)

9-Gene Signature Correlated With CD8(+) T Cell Infiltration Activated by IFN-γ: A Biomarker of Immune Checkpoint Therapy Response in Melanoma
por: Yan, Kexin, et al.
Publicado: (2021)

Integrated Analysis of the ETS Family in Melanoma Reveals a Regulatory Role of ETV7 in the Immune Microenvironment
por: Qu, Hui, et al.
Publicado: (2020)

Angioimmunoblastic T-cell lymphoma with predominant CD8+ tumor-infiltrating T-cells is a distinct immune pattern with an immunosuppressive microenvironment
por: Chen, Zihang, et al.
Publicado: (2022)

Identification and Validation of the Signatures of Infiltrating Immune Cells in the Eutopic Endometrium Endometria of Women With Endometriosis
por: Wu, Xiang-Guang, et al.
Publicado: (2021)

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis
por: Wang, Jie, et al.
Publicado: (2022)

Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer
por: Peng, Yang, et al.
Publicado: (2021)

Endostatin induces normalization of blood vessels in colorectal cancer and promotes infiltration of CD8+ T cells to improve anti-PD-L1 immunotherapy
por: Chu, Xiao-Dong, et al.
Publicado: (2022)

Functional Change of Effector Tumor-Infiltrating CCR5(+)CD38(+)HLA-DR(+)CD8(+) T Cells in Glioma Microenvironment
por: Chen, Pin-Yuan, et al.
Publicado: (2019)

Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells
por: Hu, Bin, et al.
Publicado: (2020)

Networks of CD8(+) T Cell Response Activation in Melanoma and Vitiligo
por: Fukuda, Keitaro
Publicado: (2022)

High CD8(+)tumor-infiltrating lymphocytes indicate severe exhaustion and poor prognosis in angioimmunoblastic T-cell lymphoma
por: Zhu, Qiqi, et al.
Publicado: (2023)

Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis
por: Prezzemolo, Teresa, et al.
Publicado: (2014)

Corrigendum: Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells
por: Hu, Bin, et al.
Publicado: (2022)

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal Melanoma
por: Sun, Yifang, et al.
Publicado: (2021)

Identification and experimental validation of mitochondria-related genes biomarkers associated with immune infiltration for sepsis
por: Shu, Qi, et al.
Publicado: (2023)

Identification and validation of a novel mitochondrion-related gene signature for diagnosis and immune infiltration in sepsis
por: Hao, Shuai, et al.
Publicado: (2023)

Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
por: Karkeni, Esma, et al.
Publicado: (2019)

Establishment and validation of exhausted CD8+ T cell feature as a prognostic model of HCC
por: Shi, Jihang, et al.
Publicado: (2023)

Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning
por: Ouyang, Guoqing, et al.
Publicado: (2023)

Immune-infiltrating signature-based classification reveals CD103(+)CD39(+) T cells associate with colorectal cancer prognosis and response to immunotherapy
por: Luo, Yang, et al.
Publicado: (2022)

Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells
por: Martinez-Usatorre, Amaia, et al.
Publicado: (2020)

Tumor-secreted lactate contributes to an immunosuppressive microenvironment and affects CD8 T-cell infiltration in glioblastoma
por: Wang, Zeyu, et al.
Publicado: (2023)

Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma
por: Li, Ai-lan, et al.
Publicado: (2021)

CD4CD8αα IELs: They Have Something to Say
por: Zhou, Chao, et al.
Publicado: (2019)

An estrogen response-related signature predicts response to immunotherapy in melanoma
por: Lin, Min, et al.
Publicado: (2023)

Microglia and Perivascular Macrophages Act as Antigen Presenting Cells to Promote CD8 T Cell Infiltration of the Brain
por: Goddery, Emma N., et al.
Publicado: (2021)

PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer
por: Shen, Yang, et al.
Publicado: (2020)

Tumor-Infiltrating Lymphocytes and Their Prognostic Value in Cutaneous Melanoma
por: Maibach, Fabienne, et al.
Publicado: (2020)

Identification and experimental validation of a tumor-infiltrating lymphocytes–related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma
por: Deng, Yulin, et al.
Publicado: (2022)

Tissue signatures influence the activation of intrahepatic CD8(+) T cells against malaria sporozoites
por: Morrot, Alexandre, et al.
Publicado: (2014)

Targeting Cbx3/HP1γ Induces LEF-1 and IL-21R to Promote Tumor-Infiltrating CD8 T-Cell Persistence
por: Le, Phuong T., et al.
Publicado: (2021)

Identification and validation of ferroptosis-related lncRNA signature as a prognostic model for skin cutaneous melanoma
por: Guo, Sen, et al.
Publicado: (2022)

Development and validation of immunogenic cell death-related signature for predicting the prognosis and immune landscape of uveal melanoma
por: Hu, Yuanyuan, et al.
Publicado: (2022)

Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy
por: Principe, Nicola, et al.
Publicado: (2020)

Intrahepatic infiltration of activated CD8(+) T cells and mononuclear phagocyte is associated with idiosyncratic drug-induced liver injury
por: Yang, Hyun, et al.
Publicado: (2023)

MAPK8 and CAPN1 as potential biomarkers of intervertebral disc degeneration overlapping immune infiltration, autophagy, and ceRNA
por: Zhang, Yuxin, et al.
Publicado: (2023)

Novel Immune Infiltrating Cell Signature Based on Cell Pair Algorithm Is a Prognostic Marker in Cancer
por: Zhang, Hao, et al.
Publicado: (2021)

Peritumoral Immune Infiltrate as a Prognostic Biomarker in Thin Melanoma
por: Sabbatino, Francesco, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mdikp65oo9ohdl8bmd0h01o8f0