Cargando…

AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression

The enzyme activation-induced cytidine deaminase (AID) initiates somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes, critical actions for an effective adaptive immune response. However, in addition to the benefits generated by its physiological roles, AID i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oppezzo, Pablo, Navarrete, Marcelo, Chiorazzi, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141630/ https://www.ncbi.nlm.nih.gov/pubmed/34041018 http://dx.doi.org/10.3389/fonc.2021.634383

Ejemplares similares

Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia: New Insights into Leukemic Progression
por: Prieto, Daniel, et al.
Publicado: (2017)

“Role of the B-cell receptor and the microenvironment in chronic lymphocytic leukemia''
por: Oppezzo, P, et al.
Publicado: (2013)

Measurable residual disease in chronic lymphocytic leukemia
por: Benintende, Giulia, et al.
Publicado: (2023)

The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia
por: Yuan, Chaohui, et al.
Publicado: (2017)

Telomere Dysfunction in Chronic Lymphocytic Leukemia
por: Jebaraj, Billy Michael Chelliah, et al.
Publicado: (2021)

Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia
por: Murphy, Elizabeth J., et al.
Publicado: (2017)

TGF-β/SMAD Pathway Is Modulated by miR-26b-5p: Another Piece in the Puzzle of Chronic Lymphocytic Leukemia Progression
por: Marquez, Maria Elena, et al.
Publicado: (2022)

Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia
por: Kaufman, Matthew, et al.
Publicado: (2022)

Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course
por: Bagnara, Davide, et al.
Publicado: (2021)

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
por: Rosati, Emanuela, et al.
Publicado: (2018)

Minimal Residual Disease in Chronic Lymphocytic Leukemia: A New Goal?
por: Del Giudice, Ilaria, et al.
Publicado: (2019)

Immunotherapeutic Strategies in Chronic Lymphocytic Leukemia: Advances and Challenges
por: Perutelli, Francesca, et al.
Publicado: (2022)

The evolving use of measurable residual disease in chronic lymphocytic leukemia clinical trials
por: Fisher, A., et al.
Publicado: (2023)

Human endogenous retrovirus np9 gene is over expressed in chronic lymphocytic leukemia patients
por: Fischer, Sabrina, et al.
Publicado: (2014)

Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia
por: Yi, Xue, et al.
Publicado: (2022)

Proliferative Signals in Chronic Lymphocytic Leukemia; What Are We Missing?
por: Haselager, Marco V., et al.
Publicado: (2020)

Autoimmune Cytopenias in Chronic Lymphocytic Leukemia: Focus on Molecular Aspects
por: Fattizzo, Bruno, et al.
Publicado: (2020)

CD200 and Chronic Lymphocytic Leukemia: Biological and Clinical Relevance
por: D’Arena, Giovanni, et al.
Publicado: (2020)

Precision diagnostics in chronic lymphocytic leukemia: Past, present and future
por: Mollstedt, John, et al.
Publicado: (2023)

Role of NFAT in Chronic Lymphocytic Leukemia and Other B-Cell Malignancies
por: Sana, Ilenia, et al.
Publicado: (2021)

Treatment Approaches to Chronic Lymphocytic Leukemia With High-Risk Molecular Features
por: van der Straten, Lina, et al.
Publicado: (2021)

Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force of Genome Instability
por: Zavacka, Kristyna, et al.
Publicado: (2021)

Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia
por: Wu, Xun, et al.
Publicado: (2021)

Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia
por: Wang, Zong-Han, et al.
Publicado: (2023)

Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo
por: Spaner, David E., et al.
Publicado: (2023)

Impact of Additional Chromosomal Aberrations on the Disease Progression of Chronic Myelogenous Leukemia
por: Krishna Chandran, Ramachandran, et al.
Publicado: (2019)

Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia
por: Guarente, Valerio, et al.
Publicado: (2021)

Synchronous or Metachronous Hairy Cell Leukemia and Chronic Lymphocytic Leukemia: A Case Series and Literature Review
por: Verma, Vivek, et al.
Publicado: (2017)

NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells
por: Di Ianni, Mauro, et al.
Publicado: (2018)

Time to Treatment Prediction in Chronic Lymphocytic Leukemia Based on New Transcriptional Patterns
por: Mosquera Orgueira, Adrián, et al.
Publicado: (2019)

Resistance-Associated Mutations in Chronic Lymphocytic Leukemia Patients Treated With Novel Agents
por: Sedlarikova, Lenka, et al.
Publicado: (2020)

“Double-Hit” Chronic Lymphocytic Leukemia, Involving the TP53 and MYC Genes
por: Nguyen-Khac, Florence
Publicado: (2022)

Clonal Evolution of High-Risk Chronic Lymphocytic Leukemia: A Contemporary Perspective
por: Kwok, Marwan, et al.
Publicado: (2021)

The role of allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia: A review
por: Puckrin, Robert, et al.
Publicado: (2023)

Case report: Hematologic malignancies concomitant diagnosis of hairy cell leukemia and chronic lymphocytic leukemia: A rare association
por: Valvano, Luciana, et al.
Publicado: (2022)

Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation
por: Boncompagni, Gioia, et al.
Publicado: (2022)

TH2/TH1 Shift Under Ibrutinib Treatment in Chronic Lymphocytic Leukemia
por: Puzzolo, Maria Cristina, et al.
Publicado: (2021)

Cellular Therapy in High-Risk Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter Syndrome
por: Barbanti, Maria Chiara, et al.
Publicado: (2022)

Distinct Age-Related Clinical Features and Risk Assessment in Chinese With Chronic Lymphocytic Leukemia
por: Tian, Zheng, et al.
Publicado: (2022)

IGH Translocations in Chinese Patients With Chronic Lymphocytic Leukemia: Clinicopathologic Characteristics and Genetic Profile
por: Li, Qinlu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_boltkfhmehjuvf0emtf688faqd