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Modeling Neurological Disorders in 3D Organoids Using Human-Derived Pluripotent Stem Cells

Modeling neurological disorders is challenging because they often have both endogenous and exogenous causes. Brain organoids consist of three-dimensional (3D) self-organizing brain tissue which increasingly is being used to model various aspects of brain development and disorders, such as the genera...

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Detalles Bibliográficos
Autores principales: Bose, Raj, Banerjee, Soumyabrata, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141848/
https://www.ncbi.nlm.nih.gov/pubmed/34041235
http://dx.doi.org/10.3389/fcell.2021.640212