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Myeloid Nrf2 deficiency aggravates non-alcoholic steatohepatitis progression by regulating YAP-mediated NLRP3 inflammasome signaling

Nuclear-erythroid-2-related factor 2 (Nrf2) is involved in the pathogenesis of different liver diseases. Herein, we first demonstrated that Nrf2 expression was diminished in nonalcoholic steatohepatitis (NASH) liver macrophages. In myeloid Nrf2-deficiency mice, aggravated liver steatosis and inflamm...

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Detalles Bibliográficos
Autores principales:	Wang, Peng, Ni, Ming, Tian, Yizhu, Wang, Hao, Qiu, Jiannan, You, Wenhua, Wei, Song, Shi, Yong, Zhou, Jinren, Cheng, Feng, Rao, Jianhua, Lu, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141901/ https://www.ncbi.nlm.nih.gov/pubmed/34041450 http://dx.doi.org/10.1016/j.isci.2021.102427

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