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The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis
Epigenetic regulation disorder is important in the onset and pathogenesis of inflammatory bowel disease (IBD). SETD2, a trimethyltransferase of histone H3K36, is frequently mutated in IBD samples with a high risk of developing colorectal cancer (CRC). However, functions of SETD2 in IBD and colitis-a...
Autores principales: | Liu, Min, Rao, Hanyu, Liu, Jing, Li, Xiaoxue, Feng, Wenxin, Gui, Liming, Tang, Huayuan, Xu, Jin, Gao, Wei-Qiang, Li, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141928/ https://www.ncbi.nlm.nih.gov/pubmed/34020310 http://dx.doi.org/10.1016/j.redox.2021.102004 |
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