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Identification of PI3K-AKT signaling as the dominant altered pathway in intestinal type ampullary cancers through whole-exome sequencing

BACKGROUND: The genetic landscape of intestinal (INT) and pancreatobiliary (PB) type ampullary cancer (AC) has been evolving with distinct as well as overlapping molecular profiles. METHODS: We performed whole-exome sequencing in 37 cases of AC to identify the targetable molecular profiles of INT an...

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Detalles Bibliográficos
Autores principales:	Kumari, Niraj, Singh, Rajneesh K., Mishra, Shravan K., Krishnani, Narendra, Mohindra, Samir, Raghvendra, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Pathologists and the Korean Society for Cytopathology 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141966/ https://www.ncbi.nlm.nih.gov/pubmed/33677956 http://dx.doi.org/10.4132/jptm.2021.01.23

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