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Processed HIV prognostic dataset for control experiments

This paper provides a control dataset of processed prognostic indicators for analysing drug resistance in patients on antiretroviral therapy (ART). The dataset was locally sourced from health facilities in Akwa Ibom State of Nigeria, West Africa and contains 14 attributes with 1506 unique records fi...

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Detalles Bibliográficos
Autores principales: Ekpenyong, Moses E., Etebong, Philip I., Jackson, Tenderwealth C., Udofa, Edidiong J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142042/
https://www.ncbi.nlm.nih.gov/pubmed/34041323
http://dx.doi.org/10.1016/j.dib.2021.107147
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author Ekpenyong, Moses E.
Etebong, Philip I.
Jackson, Tenderwealth C.
Udofa, Edidiong J.
author_facet Ekpenyong, Moses E.
Etebong, Philip I.
Jackson, Tenderwealth C.
Udofa, Edidiong J.
author_sort Ekpenyong, Moses E.
collection PubMed
description This paper provides a control dataset of processed prognostic indicators for analysing drug resistance in patients on antiretroviral therapy (ART). The dataset was locally sourced from health facilities in Akwa Ibom State of Nigeria, West Africa and contains 14 attributes with 1506 unique records filtered from 3168 individual treatment change episodes (TCEs). These attributes include sex, before and follow-up CD4 counts (BCD4, FCD4), before and follow-up viral load (BRNA, FRNA), drug type/combination (DTYPE), before and follow-up body weight (Bwt, Fwt), patient response to ART (PR), and classification targets (C1-C5). Five (5) output membership grades of a fuzzy inference system ranging from very high interaction to no interaction were constructed to model the influence of adverse drug reaction (ADR) and subsequently derive the PR attribute (a non-fuzzy variable). The PR attribute membership clusters derived from a universe of discourse table were then used to label the classification targets as follows: C1=no interaction, C2=very low interaction, C3=low interaction, C4=high interaction, and C5=very high interaction. The classification targets are useful for building classification models and for detecting patients with ADR. This data can be exploited for the development of expert systems, for useful decision support to treatment failure classification [1] and effectual drug regimen prescription.
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spelling pubmed-81420422021-05-25 Processed HIV prognostic dataset for control experiments Ekpenyong, Moses E. Etebong, Philip I. Jackson, Tenderwealth C. Udofa, Edidiong J. Data Brief Data Article This paper provides a control dataset of processed prognostic indicators for analysing drug resistance in patients on antiretroviral therapy (ART). The dataset was locally sourced from health facilities in Akwa Ibom State of Nigeria, West Africa and contains 14 attributes with 1506 unique records filtered from 3168 individual treatment change episodes (TCEs). These attributes include sex, before and follow-up CD4 counts (BCD4, FCD4), before and follow-up viral load (BRNA, FRNA), drug type/combination (DTYPE), before and follow-up body weight (Bwt, Fwt), patient response to ART (PR), and classification targets (C1-C5). Five (5) output membership grades of a fuzzy inference system ranging from very high interaction to no interaction were constructed to model the influence of adverse drug reaction (ADR) and subsequently derive the PR attribute (a non-fuzzy variable). The PR attribute membership clusters derived from a universe of discourse table were then used to label the classification targets as follows: C1=no interaction, C2=very low interaction, C3=low interaction, C4=high interaction, and C5=very high interaction. The classification targets are useful for building classification models and for detecting patients with ADR. This data can be exploited for the development of expert systems, for useful decision support to treatment failure classification [1] and effectual drug regimen prescription. Elsevier 2021-05-14 /pmc/articles/PMC8142042/ /pubmed/34041323 http://dx.doi.org/10.1016/j.dib.2021.107147 Text en © 2021 The Author(s). Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data Article
Ekpenyong, Moses E.
Etebong, Philip I.
Jackson, Tenderwealth C.
Udofa, Edidiong J.
Processed HIV prognostic dataset for control experiments
title Processed HIV prognostic dataset for control experiments
title_full Processed HIV prognostic dataset for control experiments
title_fullStr Processed HIV prognostic dataset for control experiments
title_full_unstemmed Processed HIV prognostic dataset for control experiments
title_short Processed HIV prognostic dataset for control experiments
title_sort processed hiv prognostic dataset for control experiments
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142042/
https://www.ncbi.nlm.nih.gov/pubmed/34041323
http://dx.doi.org/10.1016/j.dib.2021.107147
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