Cargando…

Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity

Cancer cells function as primary architects of the tumor microenvironment. However, the molecular features of cancer cells that govern stromal cell phenotypes remain unclear. Here, we show that cancer-associated fibroblast (CAF) heterogeneity is driven by lung adenocarcinoma (LUAD) cells at either e...

Descripción completa

Detalles Bibliográficos
Autores principales: Bota-Rabassedas, Neus, Banerjee, Priyam, Niu, Yichi, Cao, Wenjian, Luo, Jiayi, Xi, Yuanxin, Tan, Xiaochao, Sheng, Kuanwei, Ahn, Young-Ho, Lee, Sieun, Parra, Edwin Roger, Rodriguez-Canales, Jaime, Albritton, Jacob, Weiger, Michael, Liu, Xin, Guo, Hou-Fu, Yu, Jiang, Rodriguez, B. Leticia, Firestone, Joshua J.A., Mino, Barbara, Creighton, Chad J., Solis, Luisa M., Villalobos, Pamela, Raso, Maria Gabriela, Sazer, Daniel W., Gibbons, Don L., Russell, William K., Longmore, Gregory D., Wistuba, Ignacio I., Wang, Jing, Chapman, Harold A., Miller, Jordan S., Zong, Chenghang, Kurie, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142261/
https://www.ncbi.nlm.nih.gov/pubmed/33882319
http://dx.doi.org/10.1016/j.celrep.2021.109009