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Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin

In this study, we assessed the super relaxed (SRX) state of myosin and sarcomeric protein phosphorylation in two pathological models of cardiomyopathy and in a near-physiological model of cardiac hypertrophy. The cardiomyopathy models differ in disease progression and severity and express the hypert...

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Detalles Bibliográficos
Autores principales:	Sitbon, Yoel H., Diaz, Francisca, Kazmierczak, Katarzyna, Liang, Jingsheng, Wangpaichitr, Medhi, Szczesna-Cordary, Danuta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142263/ https://www.ncbi.nlm.nih.gov/pubmed/34014247 http://dx.doi.org/10.1085/jgp.202012801

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