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Haploinsufficiency of the NF1 gene is associated with protection against diabetes

BACKGROUND: The hereditary predisposition to diabetes is only partially explained by genes identified so far. Neurofibromatosis type 1 (NF1) is a rare monogenic dominant syndrome caused by aberrations of the NF1 gene. Here, we used a cohort of 1410 patients with NF1 to study the association of the N...

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Detalles Bibliográficos
Autores principales:	Kallionpää, Roope A, Peltonen, Sirkku, Leppävirta, Jussi, Pöyhönen, Minna, Auranen, Kari, Järveläinen, Hannu, Peltonen, Juha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Genotype-Phenotype Correlations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142421/ https://www.ncbi.nlm.nih.gov/pubmed/32571896 http://dx.doi.org/10.1136/jmedgenet-2020-107062

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