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TNF is a homoeostatic regulator of distinct epigenetically primed human osteoclast precursors

OBJECTIVES: Circulating myeloid precursors are responsible for post-natal osteoclast (OC) differentiation and skeletal health, although the exact human precursors have not been defined. Enhanced osteoclastogenesis contributes to joint destruction in rheumatoid arthritis (RA) and tumour necrosis fact...

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Detalles Bibliográficos
Autores principales:	Ansalone, Cecilia, Cole, John, Chilaka, Sabarinadh, Sunzini, Flavia, Sood, Shatakshi, Robertson, Jamie, Siebert, Stefan, McInnes, Iain B, Goodyear, Carl S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142443/ https://www.ncbi.nlm.nih.gov/pubmed/33692019 http://dx.doi.org/10.1136/annrheumdis-2020-219262

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