Cargando…

Pan-cancer characterization of metabolism-related biomarkers identifies potential therapeutic targets

BACKGROUND: Generally, cancer cells undergo metabolic reprogramming to adapt to energetic and biosynthetic requirements that support their uncontrolled proliferation. However, the mutual relationship between two critical metabolic pathways, glycolysis and oxidative phosphorylation (OXPHOS), remains...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bi, Guoshu, Bian, Yunyi, Liang, Jiaqi, Yin, Jiacheng, Li, Runmei, Zhao, Mengnan, Huang, Yiwei, Lu, Tao, Zhan, Cheng, Fan, Hong, Wang, Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142489/ https://www.ncbi.nlm.nih.gov/pubmed/34030708 http://dx.doi.org/10.1186/s12967-021-02889-0

Ejemplares similares

Multi-omics characterization and validation of invasiveness-related molecular features across multiple cancer types
por: Bi, Guoshu, et al.
Publicado: (2021)

Signatures of malignant cells and novel therapeutic targets revealed by single‐cell sequencing in lung adenocarcinoma
por: Liang, Jiaqi, et al.
Publicado: (2022)

Identification and analysis of a prognostic ferroptosis and iron-metabolism signature for esophageal squamous cell carcinoma
por: Zhao, Mengnan, et al.
Publicado: (2022)

Cisplatin resistance-related multi-omics differences and the establishment of machine learning models
por: Sui, Qihai, et al.
Publicado: (2022)

The Prognostic Value Of Lymph Node Ratio In Patients With N2 Stage Lung Squamous Cell Carcinoma: A Nomogram And Heat Map Approach
por: Bi, Guoshu, et al.
Publicado: (2019)

miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways
por: Bi, Guoshu, et al.
Publicado: (2022)

Knockdown of GTF2E2 inhibits the growth and progression of lung adenocarcinoma via RPS4X in vitro and in vivo
por: Bi, Guoshu, et al.
Publicado: (2021)

Tumor-Associated Regulatory T Cells in Non-Small-Cell Lung Cancer: Current Advances and Future Perspectives
por: Liang, Jiaqi, et al.
Publicado: (2022)

Characterization of Infiltrating Immune Cells and Secretory or Membrane-Associated Proteins in KRAS Lung Adenocarcinoma
por: Bian, Yunyi, et al.
Publicado: (2023)

Dissecting the single-cell transcriptome network in patients with esophageal squamous cell carcinoma receiving operative paclitaxel plus platinum chemotherapy
por: Chen, Zhencong, et al.
Publicado: (2021)

Reconstructing the Developmental Trajectories of Multiple Subtypes in Pulmonary Parenchymal Epithelial Cells by Single-Cell RNA-seq
por: Huang, Yiwei, et al.
Publicado: (2020)

HIF-1α switches the functionality of TGF-β signaling via changing the partners of smads to drive glucose metabolic reprogramming in non-small cell lung cancer
por: Huang, Yiwei, et al.
Publicado: (2021)

Identification of the relationship between single-cell N6-methyladenosine regulators and the infiltrating immune cells in esophageal carcinoma
por: Bian, Yunyi, et al.
Publicado: (2023)

Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas
por: Bian, Yunyi, et al.
Publicado: (2021)

Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase
por: Besskaya, Valeria, et al.
Publicado: (2023)

HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway
por: Liang, Jiaqi, et al.
Publicado: (2023)

Multi-Omics Analysis of Cancer Cell Lines with High/Low Ferroptosis Scores and Development of a Ferroptosis-Related Model for Multiple Cancer Types
por: Shan, Guangyao, et al.
Publicado: (2021)

The Effect of Diabetes Mellitus on Prognosis of Patients with Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis
por: Bi, Guoshu, et al.
Publicado: (2019)

The Significance of Secreted Phosphoprotein 1 in Multiple Human Cancers
por: Wei, Tengteng, et al.
Publicado: (2020)

Inhibition of PKA/CREB1 pathway confers sensitivity to ferroptosis in non-small cell lung cancer
por: Shan, Guangyao, et al.
Publicado: (2023)

Landscape and dynamics of single tumor and immune cells in early and advanced‐stage lung adenocarcinoma
por: Chen, Zhencong, et al.
Publicado: (2021)

Trends in the incidence, treatment, and survival of patients with lung cancer in the last four decades
por: Lu, Tao, et al.
Publicado: (2019)

Single-cell transcriptome atlas of lung adenocarcinoma featured with ground glass nodules
por: Lu, Tao, et al.
Publicado: (2020)

Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers
por: Li, Yongsheng, et al.
Publicado: (2020)

Enlarged Mediastinal Lymph Nodes in Computed Tomography are a Valuable Prognostic Factor in Non-Small Cell Lung Cancer Patients with Pathologically Negative Lymph Nodes
por: Zheng, Yuansheng, et al.
Publicado: (2020)

Multinomial and ordinal Logistic regression analyses with multi-categorical variables using R
por: Liang, Jiaqi, et al.
Publicado: (2020)

Survival and Long-Term Cause-Specific Mortality Associated With Stage IA Lung Adenocarcinoma After Wedge Resection vs. Segmentectomy: A Population-Based Propensity Score Matching and Competing Risk Analysis
por: Zhao, Mengnan, et al.
Publicado: (2019)

Genetic and microenvironmental differences in non-smoking lung adenocarcinoma patients compared with smoking patients
por: Sui, Qihai, et al.
Publicado: (2020)

Genomic And Tumor Microenvironment Differences Between Cell Cycle Progression Pathway Altered/Non-Altered Patients With Lung Adenocarcinoma
por: Shan, Guangyao, et al.
Publicado: (2022)

Compare the efficacy and safety of programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) inhibitors for advanced non-small cell lung cancer: a Bayesian analysis
por: Liang, Jiaqi, et al.
Publicado: (2020)

A nomogram to predict prognosis of patients with lung adenosquamous carcinoma: a population-based study
por: Liang, Jiaqi, et al.
Publicado: (2020)

Ligand-receptor interaction atlas within and between tumor cells and T cells in lung adenocarcinoma
por: Chen, Zhencong, et al.
Publicado: (2020)

Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker
por: Xu, Yingting, et al.
Publicado: (2023)

Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas
por: Jin, Xing, et al.
Publicado: (2021)

Nomogram to predict thymoma prognosis: A population‐based study of 1312 cases
por: Zhao, Mengnan, et al.
Publicado: (2019)

Dissecting the single-cell transcriptome network of macrophage and identifies a signature to predict prognosis in lung adenocarcinoma
por: Hu, Zhengyang, et al.
Publicado: (2023)

Comprehensive drug response profiling and pan-omic analysis identified therapeutic candidates and prognostic biomarkers for Asian cholangiocarcinoma
por: Jamnongsong, Supawan, et al.
Publicado: (2022)

Pan‑cancer analysis identified ARHGAP23 as a potential biomarker for pancreatic adenocarcinoma
por: Liu, Xiaolong, et al.
Publicado: (2023)

Development and validation of a nomogram for predicting the overall survival of patients with lung large cell neuroendocrine carcinoma
por: Xi, Junjie, et al.
Publicado: (2020)

Differential Integration of Transcriptome and Proteome Identifies Pan-Cancer Prognostic Biomarkers
por: Schwartz, Gregory W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tf5jtri7hb6oefridvd5tevvsn