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Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients

Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it...

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Autores principales: Salzano, Giovanni, Maglitto, Fabio, Bisogno, Antonella, Vaira, Luigi Angelo, De Riu, Giacomo, Cavaliere, Matteo, di Stadio, Arianna, Mesolella, Massimo, Motta, Gaetano, Ionna, Franco, Califano, Luigi, Salzano, Francesco Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142730/
https://www.ncbi.nlm.nih.gov/pubmed/34028456
http://dx.doi.org/10.14639/0392-100X-N1100
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author Salzano, Giovanni
Maglitto, Fabio
Bisogno, Antonella
Vaira, Luigi Angelo
De Riu, Giacomo
Cavaliere, Matteo
di Stadio, Arianna
Mesolella, Massimo
Motta, Gaetano
Ionna, Franco
Califano, Luigi
Salzano, Francesco Antonio
author_facet Salzano, Giovanni
Maglitto, Fabio
Bisogno, Antonella
Vaira, Luigi Angelo
De Riu, Giacomo
Cavaliere, Matteo
di Stadio, Arianna
Mesolella, Massimo
Motta, Gaetano
Ionna, Franco
Califano, Luigi
Salzano, Francesco Antonio
author_sort Salzano, Giovanni
collection PubMed
description Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery.
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spelling pubmed-81427302021-06-04 Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients Salzano, Giovanni Maglitto, Fabio Bisogno, Antonella Vaira, Luigi Angelo De Riu, Giacomo Cavaliere, Matteo di Stadio, Arianna Mesolella, Massimo Motta, Gaetano Ionna, Franco Califano, Luigi Salzano, Francesco Antonio Acta Otorhinolaryngol Ital Review Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery. Pacini Editore Srl 2021-05-14 2021-04 /pmc/articles/PMC8142730/ /pubmed/34028456 http://dx.doi.org/10.14639/0392-100X-N1100 Text en Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Review
Salzano, Giovanni
Maglitto, Fabio
Bisogno, Antonella
Vaira, Luigi Angelo
De Riu, Giacomo
Cavaliere, Matteo
di Stadio, Arianna
Mesolella, Massimo
Motta, Gaetano
Ionna, Franco
Califano, Luigi
Salzano, Francesco Antonio
Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title_full Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title_fullStr Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title_full_unstemmed Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title_short Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
title_sort obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142730/
https://www.ncbi.nlm.nih.gov/pubmed/34028456
http://dx.doi.org/10.14639/0392-100X-N1100
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