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Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Pacini Editore Srl
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142730/ https://www.ncbi.nlm.nih.gov/pubmed/34028456 http://dx.doi.org/10.14639/0392-100X-N1100 |
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author | Salzano, Giovanni Maglitto, Fabio Bisogno, Antonella Vaira, Luigi Angelo De Riu, Giacomo Cavaliere, Matteo di Stadio, Arianna Mesolella, Massimo Motta, Gaetano Ionna, Franco Califano, Luigi Salzano, Francesco Antonio |
author_facet | Salzano, Giovanni Maglitto, Fabio Bisogno, Antonella Vaira, Luigi Angelo De Riu, Giacomo Cavaliere, Matteo di Stadio, Arianna Mesolella, Massimo Motta, Gaetano Ionna, Franco Califano, Luigi Salzano, Francesco Antonio |
author_sort | Salzano, Giovanni |
collection | PubMed |
description | Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery. |
format | Online Article Text |
id | pubmed-8142730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Pacini Editore Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-81427302021-06-04 Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients Salzano, Giovanni Maglitto, Fabio Bisogno, Antonella Vaira, Luigi Angelo De Riu, Giacomo Cavaliere, Matteo di Stadio, Arianna Mesolella, Massimo Motta, Gaetano Ionna, Franco Califano, Luigi Salzano, Francesco Antonio Acta Otorhinolaryngol Ital Review Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery. Pacini Editore Srl 2021-05-14 2021-04 /pmc/articles/PMC8142730/ /pubmed/34028456 http://dx.doi.org/10.14639/0392-100X-N1100 Text en Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en |
spellingShingle | Review Salzano, Giovanni Maglitto, Fabio Bisogno, Antonella Vaira, Luigi Angelo De Riu, Giacomo Cavaliere, Matteo di Stadio, Arianna Mesolella, Massimo Motta, Gaetano Ionna, Franco Califano, Luigi Salzano, Francesco Antonio Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title | Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title_full | Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title_fullStr | Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title_full_unstemmed | Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title_short | Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
title_sort | obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142730/ https://www.ncbi.nlm.nih.gov/pubmed/34028456 http://dx.doi.org/10.14639/0392-100X-N1100 |
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